AUTOMA: a wearable device to assess the upper limb muscular activity in patients with neuromuscular disorders

Mario Milazzo 1 *, Andrea Spezzaneve 1 *, Guja Astrea 2, Francesca Giorgolo 3, Alessandro Tonacci 4, Francesco Sansone 4, Marco Calderisi 3, the Ingene Group, Raffaele Conte 4, Filippo M. Santorelli 2, Stefano Roccella 1

1 The BioRobotics Institute, Scuola Superiore Sant’Anna, Pontedera (PI), Italy; 2 IRCCS Fondazione Stella Maris, Calambrone (PI), Italy; 3 Kode s.r.l., Pisa, Italy; 4 Institute of Clinical Physiology, National Research Council of Italy (CNR), Pisa, Italy; *These authors equally contributed

DOI 10.36185/2532-1900-057

Inherited muscular dystrophies and congenital myopathies present in early childhood with progressive muscle weakness, determining severe motor limitations. Active surveillance and management of associated complications have improved ambulation, function, quality of life and life expectancy.
The need for repeatable, objective and quantitative measures to monitor the clinical course of the disease is a current issue, particularly in the new era where new flows of therapies are proposed to the patients.
In this scenario, we designed and tested a wearable device termed AUTOMA that is able to provide quantification of the muscular impairment in the upper limb upon isokinetic tests through the integration of a force sensor and an electric goniometer. This allows qualitatively estimating the muscular functions with a systematic procedure. We carried out a preliminary pilot study on 9 patients that revealed the suitability of AUTOMA as an objective measurement tool for diagnosing and monitoring neuromuscular disorders, and opens to a more extensive clinical study in which to test and validate our platform intensively.

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